Nietzsche wrote The Gay Science, which he later described as 'perhaps my most personal book', when he was at the height of his intellectual powers, and the reader will find in it an extensive and sophisticated treatment of the philosophical themes and views which were most central to Nietzsche's own thought and which have been most influential on later thinkers. These include the death of God, the problem of nihilism, the role of truth, falsity and the will-to-truth in human life, (...) the doctrine of the eternal recurrence, and the question of the proper attitude to adopt toward human suffering and toward human achievement. This volume presents the work in a new translation by Josefine Nauckhoff, with an introduction by Bernard Williams that elucidates the work's main themes and discusses their continuing philosophical importance. (shrink)

Against common misconceptions of Kant as a philosopher who neglects the emotional aspects of moral life, I show that he actually considers our emotional dispositions to be valuable tools for perfecting ourselves morally. ;I show not only that it is incumbent on us to cultivate morally beneficial emotions, but also how we can do it. Building on Kant's vague hints about what the process involves, I argue that cultivating a given feeling requires, above all, sharpening one's judgment about it, one's (...) sensitivity to its nature and to the shape it takes in one's own character in order to make responsible decisions about whether to act on the feeling and when one does choose to act on it, to express it in a way which harmonizes with one's sense of moral integrity. ;I begin with an argument showing that on Kant's mature moral theory, it is our duty to cultivate feelings which help us form a virtuous disposition. I then discuss particular feelings which are especially important in this regard. I begin with the feeling of respect for the moral law and show that it constitutes the motive of duty. Kant's "pure" moral motive--the motive of duty--is thus actually a feeling which is grounded in a rational grasp of the moral law. I then consider feelings associated with our duties toward ourselves and with our duties toward others and raise the question of how cultivated feelings figure in the virtuous character and also in relation to good willing and to morally worthy action. I show that certain "moral" feelings can become part of the motive of duty itself and so can serve as motives to morally worthy action. (shrink)

The aim of this essay is to review Friedrich Nietzsche's "The Gay Science" in English Translation. It compares and contrasts the translations by Thomas Common, Walter Kaufmann, Josefine Nauckhoff, and R. Kevin Hill. First, I argue in favor of translating the work's title "Die Fröhliche Wissenschaft" as "The Gay Science" or perhaps more precisely as "The Gay Knowledge". Nietzsche who is likely the greatest stylist in the German language wrote with philological precision and succinctness. This exactitude and awareness (...) of the shaping influence of linguistic means on the contents expressed therefore needs to be reflected throughout in any kind of rendition of Nietzsche's artful texts and the evaluation and assessment thereof. (shrink)

Nietzsche wrote The Gay Science, which he later described as 'perhaps my most personal book', when he was at the height of his intellectual powers, and the reader will find in it an extensive and sophisticated treatment of the philosophical themes and views which were most central to Nietzsche's own thought and which have been most influential on later thinkers. These include the death of God, the problem of nihilism, the role of truth, falsity and the will-to-truth in human life, (...) the doctrine of the eternal recurrence, and the question of the proper attitude to adopt toward human suffering and toward human achievement. This volume presents the work in a new translation by Josefine Nauckhoff, with an introduction by Bernard Williams that elucidates the work's main themes and discusses their continuing philosophical importance. (shrink)

Review of Nietzsche, Friedrich, The Gay Science: With a Prelude in German Rhymes and an Appendix of Songs, ed. Bernard Williams, trans. Josefine Nauckhoff, poems trans. Adrian Del Caro, Cambridge University Press, 2001.

A revolutionary new theory and call to action on animal rights, ethics, and law from the renowned philosopher Martha C. Nussbaum.

Regular polysemes are sets of ambiguous words that all share the same relationship between their meanings, such as CHICKEN and LOBSTER both referring to an animal or its meat. To probe how a distributional semantic model, here exemplified by bidirectional encoder representations from transformers (BERT), represents regular polysemy, we analyzed whether its embeddings support answering sense analogy questions similar to “is the mapping between CHICKEN (as an animal) and CHICKEN (as a meat) similar to that which maps between LOBSTER (as (...) an animal) to LOBSTER (as a meat)?” We did so using the LRcos model, which combines a logistic regression classifier of different categories (e.g., animal vs. meat) with a measure of cosine similarity. We found that (a) the model was sensitive to the shared structure within a given regular relationship; (b) the shared structure varies across different regular relationships (e.g., animal/meat vs. location/organization), potentially reflective of a “regularity continuum;” (c) some high-order latent structure is shared across different regular relationships, suggestive of a similar latent structure across different types of relationships; and (d) there is a lack of evidence for the aforementioned effects being explained by meaning overlap. Lastly, we found that both components of the LRcos model made important contributions to accurate responding and that a variation of this method could yield an accuracy boost of 10% in answering sense analogy questions. These findings enrich previous theoretical work on regular polysemy with a computationally explicit theory and methods, and provide evidence for an important organizational principle for the mental lexicon and the broader conceptual knowledge system. (shrink)

Are there epistemic duties to inquire? The idea enjoys intuitive support. However, prominent evidentialists argue that our only epistemic duty is to believe well (i.e., to have doxastically justified beliefs), and doing so does not require inquiry. Against this, I argue that evidentialists are plausibly committed to the idea that if we have epistemic duties to believe well, then we have epistemic duties to inquire. This is because on plausible evidentialist views of evidence possession (i.e., views that result in plausible (...) theories of evidentialist justification), inquiry is sometimes a necessary constitutive means of forming doxastically justified beliefs—beliefs that are proportioned to and based on one's evidence. So, either evidentialist views of evidence possession commit them to epistemic duties to inquire or they lead to independently implausible theories of evidentialist justification. My discussion also has important implications for the zetetic turn in epistemology, since I argue that evidentialists who are staunchly opposed to epistemic norms on inquiry have reason to reconsider. (shrink)

Perhaps the central question in action theory is this: what ingredient of bodily action is missing in mere behavior? But what is an analogous question for mental action? I ask this: what ingredient of active, goal-directed thought is missing in mind-wandering? My answer: attentional guidance. Attention is guided when you would feel pulled back from distractions. In contrast, mind-wandering drifts between topics unchecked. My unique starting point motivates new accounts of four central topics about mental action. First, its causal basis. (...) Mind-wandering is a case study that allows us to tease apart two causes of mental action––guidance and motivation. Second, its experiential character. Goals are rarely the objects of awareness; rather, goals are “phenomenological frames” that carve experience into felt distractions and relevant information. Third, its scope. Intentional mind-wandering is a limit case of action where one actively cultivates passivity. Fourth, my theory offers a novel response to mental action skeptics like Strawson. (shrink)

In his account of the Persian Wars, the 5th century historian Herodotus reports an exchange between the Persian monarch Xerxes and a deposed Spartan king, Demaratus, who became what Lattimore later classified as a “tragic warner” to Xerxes. On the eve of the battle of Thermopylae, Xerxes asks how a small number of free Spartiates can stand up against the massive ranks of soldiers that Xerxes has assembled. Herodotus has Demaratus reply: So is it with the Lacedaemonians; fighting singly they (...) are as brave as any man living, and together they are the best warriors on earth. Free they are, yet not wholly free; for law is their master (ἐλεύθεροι γὰρ ἐόντες οὐ πάντα ἐλεύθεροι εἰσί· ἔπεστι γάρ σφι δεσπότης νόμος), whom they fear much more than your men fear you. This is my proof—what their law bids them, that they do; and its bidding is ever the same, that they must never flee from the battle before whatsoever odds, but abide at their post and there conquer or die. (Hdt. 7.104) As the outcome of Thermopylae makes clear, Demaratus is hardly guilty of boasting. But Greek political theorists were not only fascinated by the Spartans who fought at the battle of Thermopylae in 480; they also wondered how slightly more than a century later Sparta was ignobly defeated by Thebes at the battle of Leuctra in 371, after which Spartan hegemony collapsed. How did Sparta field citizen-soldiers in the 5th century who were without parallel in their bravery and military prowess? And why did Sparta, predominantly under the same political organization, collapse just over a century later? Such are the main questions that Xenophon, Plato, Aristotle, and Plutarch—what Cartledge (1999, 313–14) has characterized as “political-theoretical” laconophiles—seek to answer in their writings about Sparta. (shrink)

This article is a précis of Mark C. Murphy’s _Divine Holiness and Divine Action_ (Oxford University Press, 2021), which offers an account of God’s holiness and of the difference this view of God’s holiness should make to our understanding of divine action.

'Updating Bertrand Russell for the 21st century... a cerebrally enjoyable survey, written with great clarity and touches of wit... The non-western section throws up some fascinating revelations' Sunday Times The story of philosophy is an epic tale: an exploration of the ideas, views and teachings of some of the most creative minds known to humanity. But since the long-popular classic Bertrand Russell's History of Western Philosophy, first published in 1945, there has been no comprehensive and entertaining, single-volume history of this (...) great intellectual journey. With his characteristic clarity and elegance A. C. Grayling takes the reader from the world-views and moralities before the age of the Buddha, Confucius and Socrates, through Christianity's dominance of the European mind to the Renaissance and Enlightenment, and on to Mill, Nietzsche, Sartre, and philosophy today. And, since the story of philosophy is incomplete without mention of the great philosophical traditions of India, China and the Persian-Arabic world, he gives a comparative survey of them too. Intelligible for students and eye-opening for philosophy readers, he covers epistemology, metaphysics, ethics, aesthetics, logic, the philosophy of mind, the philosophy of language, political philosophy and the history of debates in these areas of enquiry, through the ideas of the celebrated philosophers as well as less well-known influential thinkers. He also asks what we have learnt from this body of thought, and what progress is still to be made. The first authoritative and accessible single-volume history of philosophy for decades, remarkable for its range and clarity, this is a landmark work. (shrink)

This study considers the hiddenness of God, and the problems it raises for belief and trust in GOd. Talk of divine hiddenness evokes a variety of phenomena--the relative paucity and ambiguity of the available evidence for God's existence, the elusiveness of God's comforting presence when we are afraid and in pain, the palpable and devastating experience of divine absence and abandonment, and more. Many of these phenomena are hard to reconcile with the idea, central to the Jewish and Christian scriptures, (...) that God is deeply lovingly concerned with the lives and emotional and spiritual well-being of human creatures; and the philosophical problem of divine hiddenness ranks alongside the problem of evil as one of the two most important and widely discussed reasons for disbelieving in God. -/- The central argument of the book is that the hiddenness problem, construed as an argument against the existence of God, rests on unwarranted assumptions and expectations about God's love and goodness. In challenging these assumptions, however, Michael C Rea also considers the question of why we should accept traditional positive characterizations of God's love rather than the negative ones suggested by the phenomena of divine hiddenness. In the final four chapters, Rea aims to address this question through discussion of God's widespread experiential availability, God's loving authorization of lament and protest, and the surprising ease of seeking and participating in a relationship with God. (shrink)

In the debate on epistemic injustice, it is generally assumed that testimonial injustice as one form of epistemic injustice cannot be committed (fully) deliberately or intentionally because it involves unconscious identity prejudices. Drawing on the case of sexual violence against refugees in European refugee camps, this paper argues that there is a form of testimonial injustice—willful testimonial injustice—that is deliberate. To do so, the paper argues (a) that the hearer intentionally utilizes negative identity prejudices for a particular purpose and (b) (...) that the hearer is aware of the fact that the intentionally used prejudices are in fact prejudices. Furthermore, the paper shows how testimonial injustice relates to recognition failures both in terms of a causal as well as a constitutive claim. In fact, introducing willful testimonial injustice can support the constitutive claim of such a relation that has so far received little attention. Besides arguing for a novel form of testimonial injustice and contributing to the recent debate on the relation between epistemic injustice and recognition failures, this paper is also motivated by the attempt to draw attention to the inhumane conditions for refugees at the border of Europe as well as elsewhere. (shrink)

The article discusses the process of “conceptual borrowing”, according to which, when a new discipline emerges, it develops its technical vocabulary also by appropriating terms from other neighbouring disciplines. The phenomenon is likened to Carl Schmitt’s observation that modern political concepts have theological roots. The authors argue that, through extensive conceptual borrowing, AI has ended up describing computers anthropomorphically, as computational brains with psychological properties, while brain and cognitive sciences have ended up describing brains and minds computationally and informationally, as (...) biological computers. The crosswiring between the technical languages of these disciplines is not merely metaphorical but can lead to confusion, and damaging assumptions and consequences. The article ends on an optimistic note about the self-adjusting nature of technical meanings in language and the ability to leave misleading conceptual baggage behind when confronted with advancement in understanding and factual knowledge. (shrink)

The work of Sankary et al. (2022) provides valuable insights into the experiences of participants exiting brain device research. Empirical bioethics research such as this is critical to understandi...

At first glance, it looks like Aristotle can’t make up his mind about the ethical or moral status of non-human animals in his ethical treatises. Somewhat infamously, the Nicomachean Ethics claims that “there is neither friendship nor justice towards soulless things, nor is there towards an ox or a horse” (EN 8.11.1161b1–2). Since Aristotle thinks that friendship and justice are co-extensive (EN 8.9.1159b25–32), scholars have often read this passage to entail that humans have no ethical obligations to non-human animals. By (...) contrast, although the Eudemian Ethics denies that non-human animals can participate in “primary” friendships, EE 7.2 claims that “the other kinds of friendship are also found among animals; and it is evident that utility is present to some extent among them both in relation to humankind, in the case of tame animals, and in relation to each other” (EE 7.2.1236b3–11). Does the Nicomachean account of non-human animals contradict that of the Eudemian Ethics? Ultimately, I believe the Nicomachean account is consistent with the Eudemian account. Nonetheless, I argue that Aristotle’s treatment of non-human animals differs significantly in the two texts. My chapter explores this difference in greater detail and considers the ramifications of such a difference for our understanding of Aristotle’s place in the philosophical tradition concerning the ethical status of non-human animals. (shrink)

Recent calls for retraction of a large body of Chinese transplant research and of Dr Jiankui He’s gene editing research has led to renewed interest in the question of publication, retraction and use of unethical biomedical research. In Part 1 of this paper, we briefly review the now well-established consequentialist and deontological arguments for and against the use of unethical research. We argue that, while there are potentially compelling justifications for use under some circumstances, these justifications fail when unethical practices (...) are ongoing—as in the case of research involving transplantations in which organs have been procured unethically from executed prisoners. Use of such research displays a lack of respect and concern for the victims and undermines efforts to deter unethical practices. Such use also creates moral taint and renders those who use the research complicit in continuing harm. In Part 2, we distinguish three dimensions of ‘non-use’ of unethical research: non-use of published unethical research, non-publication, and retraction and argue that all three types of non-use should be upheld in the case of Chinese transplant research. Publishers have responsibilities to not publish contemporary unethical biomedical research, and where this has occurred, to retract publications. Failure to retract the papers implicitly condones the research, while uptake of the research through citations rewards researchers and ongoing circulation of the data in the literature facilitates subsequent use by researchers, policymakers and clinicians. (shrink)

Numerous ancient sources attest that Artemisia of Halicarnassus, a fifth-century BCE tyrant whose polis came under Persian rule in 524 BCE, figures prominently in Xerxes’ naval campaign against Greece. At least since Pompeius Trogus’ first-century BCE Philippic History, interpretations of Artemisia have juxtaposed her “virile courage” (uirilem audaciam) with Xerxes’ “womanish fear” (muliebrem timorem) primarily as a means of belittling the effeminate non-Greeks. My paper argues that although Herodotus is aware of such interpretations of Artemisia, he depicts her primarily as (...) an excellent counsel, a woman who is not only brave in battle, but who is a wonder primarily because of her intellectual excellences in deliberative rhetoric and “geo-political” strategy in the Greco-Persian world. (shrink)

Marina Sbisà has long advocated that we think of the illocutionary force of a speech act in terms of the act’s (predictable) systematic effects on the normative relationship between a speaker and her audience. Building on this idea, I argue that the hypothesis of distinctive speech act norms can be used to explain how participants in a conversation coordinate the normative expectations they have of one another in conversation. Such an explanation earns its keep by explaining how speakers render themselves (...) illocutionarily intelligible to their audiences—thereby enabling us to articulate the sense of mutuality that characterizes speech exchanges. One important upshot of my reflections is that we should reject both Austin’s thesis that the successful performance of an illocutionary act depends on audience uptake and Sbisà’s claim that Austin’s thesis is required if we are to make sense of the illocutionary dimension of speech in terms of an act’s systematic effects on participants’ normative expectations of one another. (shrink)

Theories such as effective altruism contend that people are morally obligated to give to charitable organizations that will efficiently do the most net good. The assumption is that aiding people who are most in need will create the most good; yet, it may be more inefficient to reach those most in need. In response, I outline my Inefficiency Principle in which efficiency has less moral weight when aiding those lacking in basic capabilities, and efficiency has more moral weight when aiding (...) those who are lacking in more complex capabilities. This principle acknowledges the obstacles in assisting those most in need while sustaining the moral importance of efficiency. (shrink)

Two types of formal models - landscape search tasks and two-armed bandit models - are often used to study the effects that various social factors have on epistemic performance. I argue that they can be understood within a single framework. In this unified framework, I develop a model that may be used to understand the effects of functional and demographic diversity and their interaction. Using the unified model, I find that the benefit of demographic diversity is most pronounced in a (...) functionally homogeneous group, and decreases with the increase of functional diversity. (shrink)

Divine names, i.e. the names religions use to speak of their god(s), pose a special problem to semantics. It is not only disputed whether they are proper names, descriptions, or names of kinds, the dispute between believers and non-believers over the ontological status of their bearers is a further obstacle to offering a single theory that can account for all divine names. But aboutness theory can come to the rescue here. Whatever terms divine names are, they pick out a subject (...) matter, and whereas ontology is relevant to reference, subject matters need no corresponding object in the world. Believers and non-believers can therefore agree on the name bearers’ status as topics of their conversation. (shrink)

_Winner of the Fabian Dorsch ESA Essay Prize._ Julian Dodd defends the view that, in musical work-performance practice, interpretive authenticity is a more fundamental value than score compliance authenticity. According to him, compliance with a work’s score can be sacrificed in cases where it conflicts with interpretative authenticity. Stephen Davies and Andrew Kania reject this view, arguing that, if a performer intentionally departs from a work’s score, she is not properly instantiating that work and hence not producing an authentic performance (...) of it. I argue that this objection fails. A detailed analysis of work-performance practice reveals, first, that the normative scope of interpretive authenticity encompasses the practice of composing musical versions and that, second, when performers sacrifice score compliance to maximize interpretive authenticity, they are performing the target work by means of performing a version of it. By means of the nested types theory, I then show how performances produced in this way can be properly formed instances, and hence authentic performances, of their target work. (shrink)

In the literature on expert trust, it is often assumed that track records are the gold standard for evaluating expertise, and the difficulty of expert identification arises from either the lack of access to track records, or the inability to assess them. I show, using a computational model, that even in an idealized environment where agents have a God’s eye view on track records, they may fail to identify experts. Under plausible conditions, selecting testimony based on track records ends up (...) reducing overall accuracy, and preventing the community from identifying the real experts. (shrink)

As human beings age, they become weak, fragile, and feeble. It is a slowly progressing yet complex syndrome in which old age or some disabilities are not prerequisites; neither does loss of human parts lead to frailty among the physically fit older persons. This paper aims to describe the influences of transhumanist perspectives on human‐technology enhancements and replacements in the transcendence of human frailties, including those of older persons, in which technology is projected to deliver solutions toward transcending these frailties. (...) Through technologies including genetic screening and other technological manipulations, intelligent machines and augmented humans improve, maintain, and remedy human‐linked susceptibilities. Furthermore, other technologies replace parts fabricated through inorganic‐mechanical processes such as 3D‐printing. Advancing technologies are reaching the summit of technological sophistication contributing to the transhumanist views of being human in a technological world. Technologies enhance the transcendence of human frailties as essential expressions of the symbiosis between human beings and technology in a transcendental world. (shrink)

Char et al. question the extent and degree to which machine learning applications should be treated as exceptional by ethicists. It is clear that of the suite of ethical issues raised by mac...

Background:Since 2010, the United States has experienced 228 disasters, affecting over 86 million people. Because of population shifts, the growing number of people living with chronic conditions or disabilities, and the growing number of older citizens living independently, access and service gaps often exist for those without money or other transferable resources. There is a lack of evidence regarding individual community members’ capacity to prepare for emergencies.Research objective:The purpose of this study is to highlight participant experiences in becoming better prepared (...) for emergencies and provide insight from a social justice perspective.Research design:This is a descriptive qualitative study, staying very close to the data as an end product rather than a beginning for interpretation.Participants and research context:A total of 13 low-income, uninsured, or under-insured attendees at a medical outreach clinic were interviewed.Ethical considerations:Institutional Review Board approval was obtained from the University of Texas at Tyler.Findings:Four themes emerged from the interview data: (a) evaluation of the emergency-preparedness education, (b) making emergency plans, (c) challenges in preparing for emergencies, and (d) facilitators of emergency preparedness.Discussion:Identifying the potential challenges to individual emergency preparedness among vulnerable populations is the first step in overcoming them. The capacity to comply with such measures, especially the ability of those with limited incomes and other vulnerable populations, must be considered.Conclusion:Synchronized, well-ordered assistance will close gaps in recovery and enhance efficiency in pre- and post-event aid. Theoretically, doing so will promote engaged and resilient members of society who are better able to withstand adverse events. The importance of the relationship between individual preparedness levels and the resiliency of nations supports the social justice imperative to address the needs of vulnerable populations in the mitigation and planning phase of the emergency management cycle. (shrink)

Concepts like testimonial injustice (Fricker, 2007) and testimonial violence (Dotson, 2011) articulate that marginalized epistemic agents are unjustly undermined as testifiers when dominant agents cannot or will not hear, understand, or believe their testimony. This paper turns attention away from these constraints on uptake, and towards pragmatic, social, and political constraints on how dominant audiences receive and react to testimony. I argue that these constraints can also be sources of testimonial injustice and epistemic violence. Specifically, I explore a kind of (...) injustice that I call testimonial withdrawal, which occurs when a would-be speaker chooses to remain silent because they know or reasonably expect that there is pragmatic risk associated with speaking, given their unjust marginalization. I argue that this unjustly undermines epistemic agency, and that expanding Fricker and Dotson’s umbrella concepts to accommodate this idea results in a better understanding of the moral and epistemic contours of both testimonial withdrawal and these broader categories. (shrink)

The stopping rule for a sequential experiment is the rule or procedure for determining when that experiment should end. Accordingly, the stopping rule principle (SRP) states that the evidential relationship between the final data from a sequential experiment and a hypothesis under consideration does not depend on the stopping rule: the same data should yield the same evidence, regardless of which stopping rule was used. I clarify and provide a novel defense of two interpretations of the main argument against the (...) SRP, the foregone conclusion argument. According to the first, the SRP allows for highly confirmationally unreliable experiments, which concept I make precise, to confirm highly. According to the second, it entails the evidential equivalence of experiments differing significantly in their confirmational reliability. I rebut several attempts to deflate or deflect the foregone conclusion argument, drawing connections with replication in science and the likelihood principle. (shrink)

Among mainstream political philosophers, Charles Mills is probably best known, not as the author of The Racial Contract, but for his long-running critique of ideal theory and Rawls for his association with it. Yet the critique of ideal theory that followed the publication of The Racial Contract is prefigured in that very work, where we find in inchoate form what would be further developed later on. In the book, this early formulation of the critique occupies a small part of a (...) larger, more general argument condemning mainstream political philosophy for the way that it has ignored race. In this paper, I explore the relation of the critique to this more general argument. It might be thought that the general argument leads inevitably to the critique of ideal theory. I will argue that this is not so. I will show how Mills’ more general argument can be made without taking the further step of critiquing ideal theorizing. The blame for why mainstream political philosophy has ignored race, and continues to ignore race, I will argue, should be placed elsewhere. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:The Limits of Our ObligationsRyan C. MavesDisclaimers. No funding was utilized for this manuscript. Dr. Maves is a retired U.S. Navy officer, and the opinions contained herein are his own. The opinions in this manuscript do not reflect the official opinion of the Department of the Navy, Department of Defense, nor of the U.S. Government.In 2012, I was a commander in the United States Navy, deployed to the NATO (...) Role 3 Multinational Medical Unit in Kandahar Airfield (KAF), Afghanistan. The KAF Role 3 began as a tent hospital under Canadian command, built along the flight line at Ahmad Shah Baba International Airport as [End Page 176] part of an expanding NATO base. By the time of my arrival, it was a small but capable brick-and-mortar building under U.S. Navy command, with four operating rooms, two CT scanners, and a busy intensive care unit (ICU).Not long before my deployment, the KAF Role 3 was described as one of the busiest trauma hospitals in the world. Casualties arrived every day, usually by helicopter. Blast injuries from improvised explosive devices (IEDs) were common, ranging in severity from concussions in passengers in armored vehicles, to multiple amputations from blast injuries with concomitant thoracic, abdominal, and pelvic trauma. KAF had a daytime population of over 30,000 in 2012, and our hospital was effectively the referral center for the region, so patients with non-surgical diagnoses were similarly common: myocardial infarctions, seizures, pulmonary emboli, and endemic infections, to name a few.As an infectious disease (I.D.) specialist, I functioned mainly as a hospitalist, managing patients postoperatively, but I also provided any consultative support when needed. During mass casualty events, the intensivists and I would act as backups in the trauma bay, freeing up the surgeons for the most acutely injured patients. It turned out that an I.D. doctor’s skillset lent itself well to acute trauma evaluations; we are well known for having an eye for fine details, combined with low-grade paranoia. These traits served me well during what I came to describe as “my involuntary trauma fellowship.”Our patients could be divided into five key groups: Afghan National Security Forces (ANSF, including the army and national police), non-Afghan coalition military (mostly U.S. and other NATO members), Afghan civilians, NATO civilian contract staff, and the Taliban. Our approach to each of these groups was different. For all patient groups, we would provide the same emergency care, including acute resuscitation and immediate life-saving surgery. It was after this emergency care period that our management plans diverged.For coalition forces, our next priority after acute resuscitation and stabilization was to assess whether a patient could remain in theater. Stable patients with relatively minor injuries could often undergo rehabilitation at KAF; many personnel could subsequently return to combat duty with their units. More seriously-injured patients would be transported out of Afghanistan within 24-48 hours (if not faster). Usually, this would involve stops at Bagram Airfield near Kabul and then Landstuhl Regional Medical Center in Germany before reaching a military hospital in their home countries. There were few limits on whom could be transported. Dedicated critical care air transport teams (CCATT) included intensivists, respiratory therapists, and critical care nurses, who could manage the most unstable patients on board what was effectively a flying ICU. The “lung team” in Landstuhl could fly to KAF to start patients with severe respiratory failure on extracorporeal membrane oxygenation (ECMO) and then fly them out on maximal support.NATO civilian contractors would receive comparable care, although the exact details of how they would be transported out of theater would depend on their home countries and the nature of their contract. We cared for one civilian contractor with newly-diagnosed HIV infection whom we were able to stabilize on the ventilator, get him extubated, start on initial antiretroviral therapy, and transport him home with a referral to his local HIV care program.Afghan soldiers were part of the coalition, but there was no distant home country where we could transport them. They were home. After their resuscitations and surgeries, we would arrange transfer to the Kandahar Regional... (shrink)

Although random mutation is central to models of evolutionary change, a lack of clarity remains regarding the conceptual possibilities for thinking about the nature and role of mutation in evolution. We distinguish several claims at the intersection of mutation, evolution, and directionality and then characterize a previously unrecognized category: complex conditioned mutation. Empirical evidence in support of this category suggests that the historically famous fluctuation test should be revisited, and new experiments should be undertaken with emerging experimental techniques to facilitate (...) detecting mutation rates within specific loci at an ultra‐high, individual base pair resolution. (shrink)

With an new foreword by James Warren Long renowned as one of the clearest and best introductions to ancient Greek philosophy for non-specialists, W.K.C Guthrie s The Greek Philosophers offers us a brilliant insight into the hidden foundations of Greek philosophy foundations that underpin Western thought today. Guthrie explores the great age of Greek Philosophy from Thales to Aristotle whilst combining comprehensiveness with brevity. He unpacks the ideas and arguments of Plato and Aristotle in the light of their predecessors rather (...) than their successors and describes the characteristic features of the Greek way of thinking, emphasising what he calls the cultural soil of their ideas. He also highlights the achievements of thinkers such as Pythagoras, who in contemporary accounts of Greek philosophy are frequently overlooked. Combining philosophical insight and historical sensitivity, The Greek Philosophers offers newcomers a brilliant introduction to the greatest thinkers in ancient Greek philosophy and the very origins of Western thought. ". (shrink)

What is it that permits us to see others as 'evil'? This book argues that it's our epistemological framework, which also resituates our own moral compass and reframes our moral world such that we can justify performing violent deeds, which we would readily demonize in others, as the heroics of eradicating evil. When conflict is understood positively as the confrontation of differences, an unavoidable and indeed desirable consequence of the rich tapestry of earthly life, then a discussion can open as (...) to how to navigate the countless confrontations of difference in the most skillful way. Through this lens, violence comes into view as the least skillful means of responding to, and working with, difference, since violence tends to 'rebound' and leaves both victims and perpetrators worse off—shameful and vengeful. Philosopher Wendy C. Hamblet argues that the radically polarized and oversimplified worldview that sorts the phenomena of the world into 'good guys' and 'evil others' is a framework as old as human community itself, and one that undermines people's own moral infrastructure, permitting them to take up the very acts that they would readily demonize as 'evil' in others. One's own violent responses to the human condition come to be reframed from unskillful and undesirable actions to valiant heroic reactions. In short, those who see 'evil' in others are far more likely to do 'evil,' resorting to the least skillful means for navigating difference—violence. In theory, violence is demonized as 'evil' in popular and criminological discourse and calls forth 'rebounding' like responses in the form of acts of vengeance in individuals and punitive responses in state institutions. However, punishment is itself defined as an 'evil' inflicted by a legitimate authority upon a wrongdoer in compensation for a wrong done. This leads to the conundrum that the state, as much as the vigilante, must necessarily undermine its own legitimacy by taking up the very acts that it deems as evil in its enemies and punishes in its deviant citizens. By reframing conflict positively, Hamblet introduces a new way of thinking about difference that allows the reader to appreciate (rather than tolerate) difference as a desirable feature of a multicultural, multi-religioned, multi-gendered world. This resituates the discussion of conflict such that conflict response styles can be viewed as more and less skillful means of navigating impasses in a world of differences. (shrink)